OMEGA-3 FISH OIL BENEFITS WITH REFERENCES

INFLAMMATION

  • CRP, IL-6 and TNF-α levels were reduced following omega-3 polyunsaturated fatty acids supplementation. Link to Study

  • Many favorable effects of Omega-3 are believed to result from their anti-inflammatory properties, but eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) also have inhibitory effects on immune cells and reduce proinflammatory cytokine release. Link to Study

  • On the other hand, more convincing data support the efficacy of ω-3 PUFA in reducing pain, number of tender joints, duration of morning stiffness, use of non-steroidal anti-inflammatory drugs and improving physical performance in RA patients. Link to Study

  • OM-3 CA has a broadly efficacious anti-inflammatory effect with a strong exposure–response relationship that could be beneficial in prevention and treatment of crystal arthritis, with potential applications in other IL-1β-mediated diseases. Link to Study

COGNITIVE FUNCTION

  • Improvement in short-term and working memory, immediate verbal memory, and delayed recall capability in those with mild cognitive impairment. Link to Study

  • Adjuvant omega-3 treatment was efficacious for reducing depressive symptoms in adolescents. Omega-3 also improved cognitive function, memory, and niacin skin flushing response. Link to Study

  • Increased intakes of DHA and EPA benefited mental health in older people with mild cognitive impairment.

    Link to Study

  • Significant improvement in cognitive function, functional capacity, fatigue, physical health, and daily sleepiness was observed in older adults with MCI who received high-dose omega-3 and omega-6 fatty acids supplementation combined with antioxidant vitamins, suggesting a promising potential for reducing cognitive and functional decline in this population

EYE HEALTH

  • "Our general conclusion is that there is consistent evidence to suggest that omega-3 LCPUFAs may act in a protective role against ischemia-, light-, oxygen-, inflammatory-, and age-associated pathology of the vascular and neural retina." Link to Study

  • We observed a discrete improvement in the parameters of tear function. Scientific evidence is not strong enough to systematically recommend the use of omega-3 and omega-6 fatty acids as a standalone treatment of dry eye syndrome (DES) independently from its aetiology. However, they could be considered as an effective alternative to topical treatment in patients with DES secondary to certain pathologies. Link to Study

HEART HEALTH

  • Our findings suggest that omega-3 supplementation in older individuals may yield substantial cost-savings by reducing the risk of coronary heart disease. Link to Study

  • The combination of aerobic exercise with omega-3 supplementation was observed to lower CRP and IL-6 levels in obese elderly women, indicating improved inflammatory status, which is crucial for cardiovascular health maintenance. Download Study

  • The results imply that high dietary omega-3 PUFA intake may offer benefits to cardiovascular and respiratory health in response to exposure to low-level ambient nitrogen dioxide in healthy adults. Link to Study

  • In these reports, n-3 PUFA has protected hearts through (1) anti-inflammatory effects, (2) intervention of cardiac energy metabolism, (3) modification of cardiac ion channels, (4) improvement of vascular endothelial response, and (5) modulation of autonomic nervous system activity. Download Study

REPRODUCTIVE HEALTH

  • "Increased intake of omega-3 FA can reverse the symptoms in this condition by decreasing the amount of omega-6 FA in cell membranes. An increased prostacyclin/thromboxane ratio induced by omega-3 FA can facilitate pregnancy in women with infertility problems by increasing uterine blood flow. Supplementation with omega-3 FA during pregnancy lowers the risk of premature birth and can increase the length of pregnancy and birth weight by altering the balance of eicosanoids involved in labor and promote fetal growth by improving placental blood flow. Intake of omega-3 FA during pregnancy and breast feeding may facilitate the child’s brain development. There is also some evidence that supplementation with omega-3 FA might help to prevent preeclampsia, postpartum depression, menopausal problems, postmenopausal osteoporosis, and breast cancer." Link to Study

  • Omega-3 supplements demonstrated beneficial effects for fertility in women diagnosed with PCOS. Among the overweight/obese participants, the increased clinical pregnancy rate was significant. Link to Study

  • It seems that diets rich in omega-3 fatty acids affect sperm quality and maintain the sperm membrane and mitochondria stability. Link to Study

  • In this cross-sectional study including 1679 young men in Denmark, fish oil supplements were associated in a dose-response manner with higher semen volume and total sperm count, larger testicular size, a higher calculated free testosterone to luteinizing hormone ratio, and lower follicle-stimulating hormone and luteinizing hormone levels after adjusting for confounders. Link to Study